Epilepsy surgery and tuberous sclerosis complex: special considerations
نویسندگان
چکیده
منابع مشابه
Developmental outcome of epilepsy surgery in tuberous sclerosis complex.
In Tuberous sclerosis complex (TSC), neurological dysfunction, usually in association with epilepsy, is responsible for the greatest degree of disease-related disability. Epilepsy surgery is increasingly recognized as a therapeutic option given the often medication-resistant nature of the disease. Seven subjects with medically refractory epilepsy associated with TSC, who underwent surgery at a ...
متن کاملEpilepsy surgery in tuberous sclerosis: The Dutch experience
INTRODUCTION Epilepsy associated with tuberous sclerosis complex (TSC) is drug resistant in more than half of the patients. Epilepsy surgery may be an alternative treatment option, if the epileptogenic tuber can be identified reliably and if seizure reduction is not at the expense of cognitive or other functions. We report the pre-surgical identification of the epileptogenic tuber and post-surg...
متن کاملCurrent management for epilepsy in tuberous sclerosis complex.
PURPOSE OF REVIEW This article reviews the most significant advances in the field of epilepsy associated with tuberous sclerosis complex, with emphasis on new advances in the knowledge of the pathophysiological mechanisms of epileptogenicity, progress in identifying the epileptogenic zone, and the rationale for surgical management in individuals with intractable seizures. RECENT FINDINGS Adva...
متن کاملThe natural history of epilepsy in tuberous sclerosis complex.
BACKGROUND Although epilepsy affects most patients with tuberous sclerosis complex (TSC), little is known about the natural history of epilepsy in this genetic disease. METHODS A retrospective chart review of all patients with TSC seen between January 2002 and October 2008. Charts were reviewed for a history of infantile spasms (IS), seizure other than IS, refractory epilepsy, Lennox-Gastaut ...
متن کامل"Epilepsy surgery recipes galore": in quest for the epileptogenic tuber in tuberous sclerosis complex.
Tuberous sclerosis complex (TSC) is a genetic disease, the life-long neurological morbidity of which is usually defined early in life, by epilepsy and cognitive delay that typically go hand in hand. Early onset of epilepsy is the one of the important risk factor for continuing seizures and cognitive disability later in life (Curatolo et al. 2008). Early and aggressive treatment of epilepsy is, ...
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ژورنال
عنوان ژورنال: Neurosurgical Focus
سال: 2008
ISSN: 1092-0684
DOI: 10.3171/foc/2008/25/9/e13